In the News

NIH-developed AI algorithm matches potential volunteers to clinical trials

November 18, 2024 — Such an algorithm may save clinicians time and accelerate clinical enrollment and research.

NIH-developed AI algorithm matches potential volunteers to clinical trials NIH trial of rectal microbicide for HIV prevention begins in the United States

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HIV-infected H9 T Cell

October 31, 2024 — Study will assess safety and acceptability of rectal douche for pre-exposure prophylaxis.

NIH trial of rectal microbicide for HIV prevention begins in the United States NIH clinical trial will test precision medicine treatments for myeloid cancers

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Conceptual image of blood cells on a hot pink background, along with chromosomes.

October 23, 2024 — NCI has launched myeloMATCH, a precision medicine treatment trial for people with acute myeloid leukemia and myelodysplastic syndromes.

NIH clinical trial will test precision medicine treatments for myeloid cancers Drug Combo JAKs Up Immunotherapy in Two Clinical Trials

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Jak Mechanism

August 8, 2024 — Adding a JAK inhibitor to an immune checkpoint inhibitor shrank tumors in more than half of trial participants with lung cancer or lymphoma.

Drug Combo JAKs Up Immunotherapy in Two Clinical Trials Vigorous exercise not linked to increased risk of adverse cardiac events in long QT syndrome

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Men and women run, sport training and workout, active and sports lifestyle

July 25, 2024 — NIH-supported study could lessen exercise restrictions for those with genetic heart condition.

Vigorous exercise not linked to increased risk of adverse cardiac events in long QT syndrome Immunotherapy approach shows potential in some people with metastatic solid tumors

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CT scan showing tumor before and after treatment.

July 11, 2024 — NIH researchers achieved tumor shrinkage in three of seven patients with colorectal cancers.

Immunotherapy approach shows potential in some people with metastatic solid tumors Trial Establishes Preferred Treatment for Some People with Esophageal Cancer

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Anatomic illustration of stage 2b esophageal cancer, with pop out of cancer cells in nearby lymph nodes.

July 9, 2024 — A large clinical trial looks to have settled a debate over how best to treat most people with locally advanced esophageal cancer, where the disease has spread just outside of the esophagus but not to other parts of the body.

Trial Establishes Preferred Treatment for Some People with Esophageal Cancer Experimental mRNA Vaccine Hints at Potential Against Glioblastoma

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An illustration of an enzyme unwinding a DNA strand to produce an RNA strand.

June 11, 2024 — A nanoparticle-based mRNA vaccine improved survival in dogs with brain cancer and induced rapid immune responses in a small study in humans with glioblastoma.

Experimental mRNA Vaccine Hints at Potential Against Glioblastoma U.S. clinical trials begin for twice-yearly HIV prevention injection

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HIV-1 Virus Particles Replicating

June 4, 2024 — Studies will focus on priority populations underrepresented in HIV clinical research.

U.S. clinical trials begin for twice-yearly HIV prevention injection Pembrolizumab Provides First-Ever Overall Survival Improvement in Kidney Cancer

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Anatomic illustration of stage 3 kidney cancer

May 21, 2024 — Pembrolizumab (Keytruda) treatment after surgery helped people with clear-cell renal cell carcinoma live longer in a large trial—a first for this cancer.

Pembrolizumab Provides First-Ever Overall Survival Improvement in Kidney Cancer